Ulcerative colitis medications and treatments
Bringing medications for the treatment of UC to life
While there is currently no cure for ulcerative colitis (UC), medications are available to help reduce the inflammation and relieve symptoms, allowing the colon to heal.
Medications used to treat UC include
- Aminosalicylates (5-ASAs): This class of antiinflammatory drugs is typically used to treat mild to moderate UC symptoms and help prevent relapses. They include sulfasalazine and oral formulations of mesalamine. APRISO is an aminosalicylate indicated for the maintenance of UC remission
- Corticosteroids: Also known as steroids, drugs such as prednisone, methylprednisolone, and hydrocortisone also reduce inflammation and are used to treat moderate to severely active UC. Corticosteroids suppress the immune system and are not recommended for long-term use because of significant side effects
- Immune modifiers: Immune modifiers are sometimes called immunomodulators. These drugs are used to help decrease corticosteroid usage. They lessen the inflammatory response caused by UC by working on the body's immune system
- Biologic therapies: Biologic therapies are the newest class of drugs used for people with moderate to severe ulcerative colitis. These drugs are made from antibodies that bind with certain molecules to block a particular action. Biologic drugs are administered by injection or infusion